Life Sciences Facilities
Cleanrooms & Controlled Environments
Life Sciences Facilities
Cleanrooms & Controlled Environments
Cleanrooms & Controlled Environments
What makes Cleanrooms & Controlled Environments
A cleanroom or controlled environment holds a defined level of particle, pressure and environmental control, proven and re-proven by commissioning evidence rather than by appearance.
Design considerations for Cleanroom & Controlled Environment projects
Classification and the air-change strategy, filtration and pressure cascade needed to hold it; gowning, airlock and material transfer sequencing so people and materials cannot short-circuit the barrier; wall, ceiling and floor systems with cleanable finishes, sealed junctions and flush-fitted services; temperature, humidity and, where relevant, lighting and vibration control; monitoring and alarms on pressure, particle count and environmental conditions; and plant space and access for filter changes and maintenance without breaking containment.
Regulatory context
Commissioning, qualification and requalification provision, with the documentation your quality system will rely on.
How Axentia delivers Cleanroom & Controlled Environment projects
Cleanrooms depend on the interface between the envelope, the air handling and the commissioning evidence, so the priority is single ownership of those packages. Under Construction Management we hold the cleanroom, mechanical and controls packages directly and run qualification through to documented sign-off, the approach we used to deliver five independent controlled-environment rooms and a main laboratory within a single 200 m² complex. A single room inside an existing building, under £500,000, is typically delivered with Axentia as Principal Contractor. Larger schemes where a main building contract already exists run with an external principal contractor, with Axentia programme-managing both them and your consultants.
Case Studies
Examples of Cleanrooms & Controlled Environment projects we've delivered
Cleanrooms & Controlled Environments FAQs
What are the specific requirements of a cleanroom or controlled environment?
Cleanrooms are specified by the classification you have to hold and proven by the commissioning evidence:
- Classification and the air-change strategy, filtration and pressure cascade needed to hold it.
- Gowning, airlock and material transfer sequencing so people and materials cannot short-circuit the barrier.
- Wall, ceiling and floor systems with cleanable finishes, sealed junctions and flush-fitted services.
- Temperature, humidity and, where relevant, lighting and vibration control.
- Monitoring and alarms on pressure, particle count and environmental conditions.
- Commissioning, qualification and requalification provision, with the documentation your quality system will rely on.
- Plant space and access for filter changes and maintenance without breaking containment.
I am looking to build a cleanroom or controlled environment. What sort of delivery model is best for me?
Cleanrooms depend on the interface between the envelope, the air handling and the commissioning evidence, so the priority is single ownership of those packages. Under Construction Management we hold the cleanroom, mechanical and controls packages directly and run qualification through to documented sign-off. That is the approach we used to deliver five independent controlled-environment rooms and a main laboratory within a single 200 m² complex. A single room inside an existing building, under £500,000, is typically delivered with Axentia as Principal Contractor. Larger schemes where a main building contract already exists run with an external principal contractor, with Axentia programme-managing both them and your consultants.
Talk to us about your Cleanroom & Controlled Environment project
Talk to our team about your facility, budget and timeline — we’ll recommend the right route to delivery.